Integrating genetic and gene expression data in network-based stratification analysis of cancers

BMC Bioinformatics

Table 1 Integrated ovarian subtypes hybrid scores

Rank	Gene	Subtype	Gene	Subtype	Gene	Subtype	Gene	Subtype
1	BBC3	0.159	BBC3	0.146	BBC3	0.166	BBC3	0.157
2	UBC	0.127	MAPK11	0.072	UBC	0.11	UBC	0.121
3	CCNB1	0.099	UBC	0.071	JAK3	0.097	RB1	0.097
4	YWHAB	0.099	ORC5	0.068	HRAS	0.096	KRAS	0.091
5	DHX9	0.098	NOTCH3	0.068	GSK3A	0.093	HRAS	0.091
6	HSP90AB1	0.097	EIF3E	0.066	IL6	0.091	LIF	0.091
7	TNF	0.096	PPP3R1	0.066	RB1	0.091	JAK3	0.091
8	RB1	0.095	NAP1L1	0.065	SMC3	0.09	MYL7	0.089
9	TERT	0.095	IFNG	0.064	STAT3	0.09	A2M	0.088
10	HRAS	0.092	PPP2R5B	0.064	KRAS	0.09	FN1	0.088

The genes with the highest mean hybrid score across the networks of the patients in ovarian cancer subtypes using integrated profiles. BBC3 and UBC are relevant high-scoring genes across all 4 subtypes

ISSN: 1471-2105